A p-tert-butylthiacalix[4]arene-based polydentated ligand with four Schiff base units on 1,3-alternate position at lower rim has been prepared in three steps,which coordinated to copper ion to form a novel dicopper complex.The structures of the polydentated thiacalixarene ligand and copper complex were fully characterized by spectroscopy and X-ray single crystal diffraction method.
The polysubstituted thiophene derivatives were conveniently prepared by the four-component reactions of 1,3-thiazolidinedione, aromatic aldehydes, cyanoacetamide and cyclic secondary amines such as pyrrolidine, mor- pholine and piperidine. The reaction mechanism is believed to involve domino reactions of Knoevenagel condensation, Michael addition, ring-opening and recyclization of 1,3-thiazolidinedione.
The calix[4]arene-based podands which incorporates two terpyridinyl functional groups derived from the alkylatiorl reactions of 4-（co-chloroalkoxyphenyl）-2,2＇：6＇,2＂-terpyridine in 1,3-alternate position at lower rim have been prepared in moderate yields. The structures of four pyridyl compounds were determined by X-ray single crystal diffraction method. The complexing properties of bis-terpyridinyl-calix[4]arenes for transition metal ions were inves- tigated by fluorescence spectra. Bis-terpyridinyl-calix[4]arenes gave a more efficient fluorescent sensing ability to Zn2＋.
Complex bridged 1,3-oxazabicycles and 1,4-disubstituted 1,10-phenanthroline derivatives were efficiently prepared by the reactions of N-methyl or N-benzylphenanthrolinium halides with cyclic 1,3-dicarbonyl compounds in a K2CO3/CH3CN system.
An efficient synthetic protocol for the 1,4-diaryl-1,4-dihydropyridines was developed via the domino four-component reaction of arylamine,acetylenedicarboxylate,aromatic aldehyde and ethyl acetoacetate.The reaction mechanism involves the formation of β-enamino ester and its sequential Michael addition to arylidene acetoacetate.
The three-component reaction of aromatic aldehyde,malononitrile and aliphatic amine in a mixed solvent of methanol and water exhibited very interesting molecular diversity and gave the derivatives of polysubstituted N-methyldihydropyridines,2-dialkylaminopyridines and 2-methoxypyridines as main products according to the structure of aliphatic amines used.
The 1,4-diazabicyclo[2.2.2]octane（DABCO） catalyzed reaction of cyclohexane-1,3-dione or dimedone with various aldehydes in acetonitrile resulted in the polysubstituted tetraketones, spiro dihydrofurans or 1,8-dioxo-xanthenes derivatives as main products respectively according to the structure of reactants and reaction conditions.
A series of p-tert-butylcalix[4]arene 1,3-distal and monosubstituted semicarbazones and thiosemicarbazones was preparedd by acid catalyzed condensation reaction of active calixarene aldehydes with semi- carbazide and thiocarbazide in methanol. One representative single crystal was determined by X-ray dirraction method, which shows that calixarene exists in cone configuration and intramolecular hydrogen-bands exist in the crystal.
LIU ZhenmingLIU DongmeiWANG JinxiangSUN JingYAN Chaoguo
